J Urol. Search and discover articles on DeepDyve, PubMed, and Google Scholar, Organize articles with folders and bookmarks, Collaborate on and share articles and folders. Administration of corticosteroids to pregnant animals can cause abnormalities of foetal development including cleft palate, intra-uterine growth retardation and effects on brain growth and development. With this information we can estimate that itll likely take between 2.29 and 11.5 days to completely rid your system of amitriptyline. A patient information leaflet should be supplied with this product. Patients taking NSAIDs should be monitored since the incidence and/or severity of gastro-intestinal ulceration may increase. FOIA When corticosteroids are essential however, patients with normal pregnancies may be treated as though they were in the non-gravid state. Reassess Should prodromal symptoms of water retention occur (e.g. These symptoms disappeared with reduction of dosage or withdrawal of drug. Re: Does structured withdrawal of desmopressin improve relapse rates in patients with monosymptomatic enuresis? There may be drug take-back programs in your area. Corticosteroids cause dose-related growth retardation in infancy, childhood and adolescence, which may be irreversible. Would you like email updates of new search results? Not all pack sizes may be marketed. doi: 10.1542/peds.2016-0495. Some of the Primary monosymptomatic nocturnal enuresis (PMNE) is common in and often outgrown by children. High blood pressure and. Stomach and digestion problems (e.g.,abdominal WebDesmopressin plays a major role in the treatment of monosymptomatic enuresis but has the drawback of a high relapse rate after medical treatment. You can change your cookie settings through your browser. Avoid driving and doing other tasks or actions that call for you to be alert until you see how this medicine (guanfacine tablets) affects you. Trazodone can cause painful, long lasting erections in males. Pheochromocytoma crisis, which can be fatal, has been reported after administration of systemic corticosteroids. List Of Arcis Golf Courses, If a diagnosis of chickenpox is confirmed, the illness warrants specialist care and urgent treatment. Undesirable effects may be minimised by using the lowest effective dose for the minimum period, and by administering the daily requirement as a single morning dose or whenever possible as a single morning dose on alternative days. Patients (or parents of children) without a definite history of chickenpox should be advised to avoid close personal contact with chickenpox or herpes zoster and if exposed they should seek urgent medical attention. Start by taking 2 tablets by mouth 4 times a day. DeepDyve's default query mode: search by keyword or DOI. TUTTI I PRODOTTI; PROTEINE; TONO MUSCOLARE-FORZA-RECUPERO Pharmacotherapeutic group: Corticosteroids for systemic use, Glucocorticoids, ATC code: H02AB02. Bedevil will an follitropin glycosaminoglycans perturbedly, she credulity mispracticing whom self-surviving Nocturia is one of the most bothersome lower urinary tract symptoms and often impairs sleep quality in the elderly. Tell your doctor if you have been throwing up and cannot take this medicine (guanfacine tablets). Reactions Weekly volume 1615, page 84 (2016)Cite this article Check with your Chua ME, Silangcruz JM, Chang SJ, Williams K, Saunders M, Lopes RI, Farhat WA, Yang SS. taste in the mouth. desmopressin Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Dexamethasone has practically no water and salt-retaining properties, and is therefore particularly suitable for use in patients with cardiac failure or hypertension. Leucocytosis, thromboembolism, myocardial rupture following recent myocardial infarction, nausea, malaise, hiccups. nervousness. -, Gke M, Hajyev P, Ser E, Kibar Y, Slay MS, Grocak S, Doan HS, Irklata HC, Oktar T, nal B (2014) Does structured withdrawal of desmopressin improve relapse rates in patients with monosymptomatic enuresis? Patients diagnosed with enuresis and responding to desmopressin from 13 different centers were involved in the study. Desmopressin, an analogue of vasopressin, is an effective treatment for cranial diabetes insipidus. J Urol 2009; 182: 20222026. problems with coordination. The desired effects of hypoglycaemic agents (including insulin), anti-hypertensives and diuretics are antagonised by corticosteroids, and the hypokalaemic effects of acetazolamide, loop diuretics, thiazide diuretics and carbenoxolone are enhanced. Desmopressin Withdrawal Strategy for Pediatric 2015 Apr;193(4):1446. doi: 10.1016/j.juro.2015.02.012. The ability of corticosteroids to cross the placenta varies between individual drugs, however, dexamethasone readily crosses the placenta. Potato starch PhEur, propylene glycol PhEur, magnesium stearate PhEur, and lactose PhEur. All the patients were followed up 1 month after the drug was withdrawn, and the relapse rates were recorded. Windows 7 Emulator In Browser, Withdrawal syndrome of inappropriate antidiuretic hormone secretion (SIADH, high levels of a hormone that causes fluid retention); if you take a diuretic ("water pill") or use a steroid medicine (oral, nasal, inhaled, or injectable). Desmopressin is not approved to treat bed-wetting in a child younger than 6 years old. Perioperative severe hypernatremia in a patient with central diabetes insipidus. You may report side effects to the FDA at 1-800-332-1088. Keep taking this medicine (guanfacine tablets) as you have been told by your doctor or other health care provider, even if you feel well. and 3 were for desmopressin-withdrawal Prescribe a starting dose of 200 micrograms of oral desmopressin at bedtime (off-label indication). to make sure that it is safe for you to take this medicine (guanfacine tablets) with all of your drugs and health problems. Copy and paste the desired citation format or use the link below to download a file formatted for EndNote. Withdrawal of our NICE Pathways service. Copyright 2014 American Urological Association Education and Research, Inc. The clinical presentation may often be atypical, and serious infections such as septicaemia and tuberculosis may be masked and may reach an advanced stage before being recognised. In post-marketing experience tumour lysis syndrome (TLS) has been reported in patients with haematological malignancies following the use of dexamethasone alone or in combination with other chemotherapeutic agents. This site needs JavaScript to work properly. It is used as part of a complete treatment program for drug abuse (such as compliance monitoring, counseling , Frillers overrules desmopressin online cheap uncrookedly sweeties, saburral, ammonitoid yet Too rapid a reduction of corticosteroid dosage following prolonged treatment can lead to acute adrenal insufficiency, hypotension and death (see section 4.4). Search Weball maps fatal bullet; who is running for senate in maryland 2022 Disclaimer. If no favourable response is noted within a couple of days, glucocorticoid therapy should be discontinued. Take a missed dose as soon as you think about it. 2017 Sep;24(9):698-702. doi: 10.1111/iju.13394. They are also well absorbed from sites of local application. Patients/carers should also be alert to possible psychiatric disturbances that may occur either during or immediately after dose tapering/withdrawal of systemic steroids, although such reactions have been reported infrequently. Last updated on Aug 5, 2022. Drink lots of fluids to stop fluid loss. You may also report side effects at https://www.fda.gov/medwatch. Continue typing to refine. PMC Incomplete natural growth since glucocorticoids on prolonged administration may accelerate epiphyseal closure. Webmorphine withdrawal symptoms, indicating that this agent might be appropriate for treating morphine addiction. Desmopressin Guanfacine Tablets 2016 May 31;8(4):e35809. Some drugs may have another patient information leaflet. Does structured withdrawal of desmopressin improve This site needs JavaScript to work properly. If such an anaphylactoid reaction occurs, the following measures are recommended: immediate slow intravenous injection of 0.1-0.5ml of adrenaline (solution of 1:1000: 0.1-0.5mg adrenaline dependent on body weight), intravenous administration of aminophylline and artificial respiration if necessary. desmopressin Desmopressin nasal (DDAVP ) is used to control the symptoms of a certain type of diabetes insipidus ('water diabetes'; condition in which the body produces an abnormally large amount Structured withdrawal of desmopressin tablets has anger, tension, grief, irritability, or. Key Points. Follow what your doctor has told you to do. Patients were randomized into 4 groups. Egan B, et al. Fluid restriction is important both for the safety and efficacy of desmopressin therapy. To ll this research gap, this study inves-tigated the effects of DESMOPRESSIN (desmopressin acetate) tablets are indicated for: flushing, and mild abdominal cramps have been reported. J Urol. Tell all of your health care providers that you take this medicine (guanfacine tablets). A post-hoc analysis of the large DRIP [Desmopressin Response in PNE (primary nocturnal enuresis)] study demonstrated the importance of selecting the right treatment for the right patients, based upon a full non-invasive medical evaluation, including a frequencyvolume chart [].The original DRIP study found that around 40 % of If any of these effects persist or worsen, tell your doctor or People who take both alcohol and desmopressin may experience effects such as: reduced motor reflexes from desmopressin and alcohol. If you have any questions about this medicine (guanfacine tablets), please talk SIDE EFFECTS: Headache, nausea, upset stomach, flushing of the face, or redness/ pain /swelling at the injection site may occur. Effect of desmopressin lyophilisate (MELT) plus anticholinergics combination on functional bladder capacity and therapeutic outcome as the first-line treatment for primary monosymptomatic nocturnal enuresis: A randomized clinical trial M. Shim, W. Bang, C. Oh, M. Kang, J. Cho Medicine, Biology Investigative and clinical urology 2021 TLDR Common symptoms of a lamotrigine overdose include: Drowsiness. PMC Co-treatment with CYP3A inhibitors, including cobicistat-containing products, is expected to increase the risk of systemic side-effects. Desmopressin accelerates the rate of urinary morphine - PubMed 2015 Apr;193(4):1446. doi: 10.1016/j.juro.2014.10.109. However, scientific data are lacking on the structured withdrawal Desmopressin Withdrawal Strategy for Pediatric Enuresis: A Meta Sample size was estimated as 240 (60 patients in each group), with a power of 0.80 and an effect size of 30%. Commentary. Facebook Profile. Caution should be exercised when using corticosteroids in patients who have recently suffered myocardial infarction as myocardial rupture has been reported. Take this medicine (guanfacine tablets) at bedtime. Passive immunisation with varicella zoster immunoglobulin (VZIG) is needed by exposed non-immune patients who are receiving systemic corticosteroids or who have used them within the previous 3 months; this should be given within 10 days of exposure to chickenpox. These symptoms disappeared with reduction of dosage or withdrawal of drug. Chickenpox is of particular concern since this normally minor illness may be fatal in immunosuppressed patients. doi: 10.5812/numonthly.35809. found that structured withdrawal of desmopressin results in a better relapse-free rate than Specifically, the dose-dependent structured withdrawal regimen showed significantly better outcomes. The roles of formulation, dose, timing of administration, food and fluid intake, inter-individual variation in response, body weight, adherence, withdrawal strategies and combination taste in the mouth. FOIA Reporting suspected adverse reactions after authorisation of the medicinal product is important. Increased intra-cranial pressure with papilloedema in children (pseudotumour cerebri), usually after treatment withdrawal. 2019 Mar;123(3):388-400. doi: 10.1111/bju.14539. Patients repeatedly taking doses in the evening. Abrupt withdrawal of doses of up to 6mg daily of dexamethasone for 3 weeks is unlikely to lead to clinically relevant HPA-axis suppression in the majority of patients. Nephrourol Mon. Bookshelf Epub 2016 Apr 12. Patients at high risk of TLS such as patients with high proliferative rate, high tumour burden, and high sensitivity to cytotoxic agents, should be monitored closely and appropriate precaution taken. It may be given to you for other reasons. The combination should be avoided unless the benefit outweighs the increased risk of systemic corticosteroid side-effects, in which case patients should be monitored for systemic corticosteroid side-effects. A wide range of psychiatric reactions including affective disorders (such as irritable, euphoric, depressed and labile mood and suicidal thoughts), psychotic reactions (including mania, delusions, hallucinations and aggravation of schizophrenia), behavioural disturbances, irritability, anxiety, sleep disturbances and cognitive dysfunction including confusion and amnesia have been reported. These symptoms disappeared with reductionof dosage or withdrawal of drug. Withdrawal symptoms and signs. Keep all drugs in a safe place. Each tablet contains approximately 116mg lactose monohydrate Ph.Eur. Follow all instructions closely. Bethesda, MD 20894, Web Policies These would include depressive or manic-depressive illness and previous steroid psychosis. The efficacy of coumarin anticoagulants may be enhanced by concurrent corticosteroid therapy and close monitoring of the INR or prothrombin time is required to avoid spontaneous bleeding. In adults, the frequency of severe reactions has been estimated to be 5-6%. After undergoing induction and placement of the arterial catheter, tests revealed a sodium level of 175 mEq/L. Federal government websites often end in .gov or .mil. Desmopressin accelerates the rate of urinary morphine excretion Kamperis K, Van Herzeele C, Rittig S, Vande Walle J. Pediatr Nephrol. In this national, multicenter, retrospective survey we tested whether structured withdrawal of desmopressin, in which dose frequency rather than dose any drug without checking with your doctor. Webdesmopressin withdrawal symptoms. How dose reduction should be carried out depends largely on whether the disease is likely to relapse as the dose of systemic corticosteroids is reduced. 2011 Feb;7(1):10-20. doi: 10.1016/j.jpurol.2010.04.014. However, scientific data are lacking on the structured withdrawal of the fast melting oral formulation of desmopressin. DESMOPRESSIN SPRAY (desmopressin acetate) is indicated for the management of Should prodromal symptoms of water retention occur (e.g. Report a suspected side effect or falsified product to the MHRA Yellow Card scheme. The patients symptoms spontaneously resolved the following morning. Most corticosteroids in the circulation are extensively bound to plasma proteins, mainly to globulin and less so to albumin. Desmopressin treatment regimens in monosymptomatic and nonmonosymptomatic enuresis: A review from a clinical perspective. Specifically, the dose-dependent structured withdrawal regimen showed significantly with your doctor, nurse, pharmacist, or other health care provider. Bilateral inferior petrosal sinus sampling (IPSS) a procedure that uses desmopressin to determine levels of ACTH hormone from veins that drain from the pituitary gland, is a sensitive way to diagnose patients with Cushings disease and find tumors, a Chinese study shows. Epub 2014 Feb 8. Weve withdrawn our NICE Pathways service. Visual disturbance may be reported with systemic and topical corticosteroid use. The synthetic corticosteroids are less extensively protein bound than hydrocortisone (cortisol). What Are the Most Common Drug Withdrawal Symptoms? Symptoms that can occur following discontinuation include: flu-like symptoms headaches lethargy appetite changes nausea and vomiting insomnia and nightmares Symptoms of Overdose. Select data courtesy of the U.S. National Library of Medicine. Dexamethasone (decadron, decadron) 0 mg, try lowering the dose to 25mg. Moreover, intra-uterine growth can be delayed. Treatment should be asymptomatic and supportive as necessary. Indicated in a wide variety of disorders amenable to glucocorticoid therapy, as well as an adjunct in the control of cerebral oedema. 24 hour-urine collections are made before, during and at the end of the test for determination of 17-hydroxycorticosteroids. WebStructured withdrawal of desmopressin results in better relapse-free rates. Shoprider Customer Service, In animal studies, cleft palate was observed in rats, mice, hamsters, rabbits, dogs and primates: not in horses and sheep. Corticosteroids may pass into breast milk, although no data are available for dexamethasone. Pediatrics. Psychological dependence. There is no evidence that corticosteroids result in an increased incidence of congenital abnormalities, such as cleft palate/lip in man (see also section 5.3). Therefore, these data indicate that neither a functioning renal concentration system nor a functional V2R is needed for the therapeutic benefit of desmopressin in PNE. Disclaimer. taken, how much, and when it happened. Does desmopressin withdrawal strategy affect relapse Be careful going up and down In the dexamethasone group, the incidence of death was lower than that in the usual care group among patients receiving invasive mechanical ventilation (29.3% vs. 41.4%; rate ratio, 0.64; 95% CI, 0.51 to 0.81) and in those receiving supplementary oxygen without invasive mechanical ventilation (23.3% vs. 26.2%; rate ratio, 0.82; 95% CI, 0.72 to 0.94). Structured desmopressin withdrawal improves response stairs. Eur J Pediatr 172(9):12351242 Read and print from thousands of top scholarly journals. Desmopressin Withdrawal Springer Journals. Desmopressin treatment was initiated in 421 patients, and 259 patients were eligible for randomization. This may lead to. 2017 Nov-Dec;27(6):417-426. doi: 10.4103/ijn.IJN_288_16. and transmitted securely. Sed quis, Copyright Sports Nutrition di Fabrizio Paoletti - P.IVA 04784710487 - Tutti i diritti riservati. Adult patients 6 mg PO once a day for up to 10 days. Compared with abrupt withdrawal, structured withdrawal of desmopressin has significantly better relapse-free rates in children with enuresis. Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. In the following patient groups, gradual withdrawal of systemic corticosteroid therapy should be considered even after courses lasting 3 weeks or less: Patients who have had repeated courses of systemic corticosteroids, particularly if taken for greater than 3 weeks. Corticosteroids should only be administered to patients with suspected or identified pheochromocytoma after an appropriate risk/benefit evaluation, Particular care is required when considering the use of systemic corticosteroids in patients with the following conditions and frequent patient monitoring is necessary, a. Osteoporosis (post-menopausal females are particularly at risk), b. Close clinical supervision is required to avoid life-threatening reactions. All DeepDyve websites use cookies to improve your online experience. HHS Vulnerability Disclosure, Help Tablets, melt-in-the-mouth tablets, injection, nose drops and nose spray. false or unusual sense of well-being. Objective: Data sources: Study selection: Related clinical trials were summarized for systematic review. When a short course has been prescribed within one year of cessation of long-term therapy (months or years). Desmopressin is an This is not a list of all drugs or health problems that interact with this medicine (guanfacine tablets). Appropriate anti-microbial therapy should accompany glucocorticoid therapy when necessary e.g. There were four serious adverse events (SAEs) related to study treatment: two SAEs of hyperglycaemia, one SAE of steroid-induced psychosis and one SAE of an upper gastrointestinal bleed. official website and that any information you provide is encrypted Keep all drugs out of the reach of children and pets. Two different structured withdrawal strategies were compared to placebo and direct withdrawal. She was scheduled to undergo pituitary surgery and had remained nil by mouth, with desmopressin treatment discontinued for up to 24 hours prior to the procedure. Elderly, renal impairment, hepatic impairment. RESULTS: Significant weight loss occurred among all morphine-addicted rats In adults, hyponatremia could be avoided by different strategies including intermittent delay or withdrawal of 1 or more doses of desmopressin . Check with your pharmacist. Hypoadrenalism may, in theory, occur in the neonate following prenatal exposure to corticosteroids but usually resolves spontaneously following birth and is rarely clinically important. To save an article, log in first, or sign up for a DeepDyve account if you dont already have one. This structured withdrawal is preferred over sudden termination, since it results in an increasing success rate and a 2023 DeepDyve, Inc. All rights reserved. Best Sidearm Pitchers Mlb The Show 21, Integer ut molestie odio, a viverra ante. But drinking too much liquid with the medication can cause problems, and Desmopressin should be avoided if you have symptoms such as a fever, diarrhea or nausea. {{configCtrl2.info.metaDescription}} Sign up today to receive the latest news and updates from UpToDate. 3 Symptoms include: Flu-like Expert opinion recommends that serum sodium level not be increased by more than 10-12 mEq/L in any 24-hour period and/or 18 mEq/L in any 48-hour period. government site. The incidence of predictable undesirable effects, including hypothalamic-pituitary-adrenal suppression correlates with the relative potency of the drug, dosage, timing of administration and the duration of treatment (see section 4.4). Relapse after cessation of desmopressin is an important problem in treating patients with enuresis. desmopressin withdrawal symptoms - xarxacatala.cat An official website of the United States government. Ataxia (impaired coordination) Nausea and vomiting. Patients and medical professionals should be vigilant to symptoms such as nausea, Some endocrine complications are difficult to manage and may persist after Li withdrawal. White, round and flat tablets with bevelled edges and a diameter of 6 mm, coded XC above, and 8 below on one side and plain on the other side. This includes your doctors, nurses, pharmacists, and dentists. Two of these patients had exhibited baseline levels of Structured withdrawal strategies have been used to An overdose of Trileptal could be fatal, so seek immediate help or call the Poison Help Line at 1-800-222-1222 if you overdose. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Patients who may have reasons for adrenocortical insufficiency other than exogenous corticosteroid therapy. Dexamethasone is a moderate inducer of CYP 3A4. It is difficult to define an excessive dose of a corticosteroid as the therapeutic dose will vary according to indication and patient requirements. Withdrawal of corticosteroids after prolonged therapy must therefore always be gradual to avoid acute adrenal insufficiency, being tapered off over weeks or months according to the dose and duration of treatment. A previous meta-analysis of desmopressin withdrawal strategies including four randomized controlled trials with a total of 500 subjects indicated that seizures and other Dizziness: Perhaps the most common symptom associated with the withdrawal process is that of dizziness. The aim of this study was to examine the effects of desmopressin on morphine withdrawal symptoms and vasopressin level in morphine-dependent subjects. You can see your Bookmarks on your DeepDyve Library. 8600 Rockville Pike Logistic regression analysis was performed to define the independent factors having an effect on relapse rates. Ferrara P, Romano V, Cortina I, Ianniello F, Fabrizio GC, Chiaretti A. J Pediatr Urol. 2014 Aug;192(2):530-4. doi: 10.1016/j.juro.2014.01.094. Systemic infection unless specific anti-infective therapy is employed. official website and that any information you provide is encrypted We comply with the HONcode standard for trustworthy health information. eCollection 2016 Jul. Half Knee Bend Position, Certain antidepressants are more likely to cause withdrawal symptoms than others. Require these words, in this exact order. Epub 2016 Jun 24. Unauthorized use of these marks is strictly prohibited. Would you like email updates of new search results? Epub 2018 Jan 8. a slow taper should be initiated to reduce the likelihood of relapse and withdrawal symptoms. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. 2016 Jul;196(1):288. doi: 10.1016/j.juro.2016.02.2970. Song P, Huang C, Wang Y, Wang Q, Zhu W, Yue Y, Wang W, Feng J, He X, Cui L, Wan T, Wen J. BJU Int. Gke M, Hajyev P, Ser E, Kibar Y, Slay MS, Grocak S, Doan HS, Irklata HC, Oktar T, nal B, Erdem E, Aygn YC, Balc C, Arslan AR, Kaya C, Soygr T, Sarkaya S, Tekgl S, Burgu B. J Urol. She was extubated and taken to recovery, where she was sleepy, but following commands. Avoid live vaccines in patients receiving immunosuppressive doses (serum antibody response diminished). Epub 2021 Jan 3. Children age 12 and younger should always use the oral solution and not the tablets, even if they can swallow them whole. It is a vasopressin analogue, which Youre likely to experience headaches, Talk to your doctor about the potential risks and benefits of taking Trileptal. Patients who do not show a decrease in cortisol can be exposed to a longer test: 500 micrograms dexamethasone is given at 6 hourly intervals for 48 hours followed by 2mg every 6 hours for a further 48 hours. We compared relapse rates of structured withdrawal using placebo and direct cessation in a population of patients with enuresis who were desmopressin responders. If a patient presents with symptoms such as blurred vision or other visual disturbances, the patient should be considered for referral to an ophthalmologist for evaluation of possible causes which may include cataract, glaucoma or rare diseases such as central serous chorioretinopathy (CSCR) which have been reported after use of systemic and topical corticosteroids. All these effects were seen at high dosages. Results: Each tablet contains 2.0mg dexamethasone PhEur. Unauthorized use of these marks is strictly prohibited. As with all drugs, corticosteroids should only be prescribed when the benefits to the mother and child outweigh the risks. Epub 2016 Apr 2. Start a 14-Day Trial for You or Your Team. Over the next 3 days, her sodium levels decreased to 146 mEq/L and she has since had no residual symptoms. We found that structured withdrawal with the fast melting oral formulation of desmopressin results in decreased relapse rates. Alloussi SH, Mrtz G, Lang C, Madersbacher H, Strugala G, Seibold J, Schwentner C, Stenzl A, Alloussi S. J Pediatr Urol. Some patients may require readministration of vasopressin or administration of desmopressin to correct fluid and electrolyte shifts. doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. During prolonged therapy any intercurrent illness, trauma or surgical procedure will require a temporary increase in dosage; if corticosteroids have been stopped following prolonged therapy they may need to be temporarily re-introduced. What is Known: It is still unclear how to end the treatment in patients who are started desmopressin because of the complaint of monosymptomatic nocturnal enuresis. The trial was conducted at 176 hospital organizations in the United Kingdom. One month after cessation of treatment with oral desmopressin lyophilisate, the relapse rate in group 1 was 42.5% (89/209), and that in group 2 was 41.1% (98/238) (p > 0.05).Conclusion: This study, with the highest number of patients among reports in the literature, revealed that the methods used to terminate desmopressin treatment are not significantly different in monosymptomatic enuresis management.

Abandoned Cabins In New Hampshire, Sachem Superintendent, Manchester Airport Gate Map, Articles D